Cic edizioni internazionali
Oral Implantology

GENETIC SUSCEPTIBILITY AND PERIODONTAL DISEASE: A RETROSPECTIVE STUDY ON A LARGE ITALIAN SAMPLE

Original research, 20 - 27
doi: 10.11138/orl/2017.10.1.020
Tag this article
Abstract
Enhanced HTML Full text PDF
Background. Periodontal disease (PD) is a multifactorial illness in which environment and host interact. The genetic component plays a key role in the onset of PD. In fact the genetic compound can modulate the inflammation of the mucous membranes and the loss of alveolar bone. The genetics of PD is not well understood. Previous studies suggest a strong association between PD occurrence and individual genetic profile. The role of genetic susceptibility could impact on the clinical manifestations of PD, and consequently on prevention and therapy.
Materials and methods. Genetic polymorphisms of VRD, IL6 and IL10 were investigated in Italian adults affected by PD. 571 cases classified according the criteria of the American Academy of Periodontology were included. All patients were Italian coming from three areas according to italian institute of statistics (ISTAT) (www.istat.it/it/archivio/regioni). The sample comprised 379 patients from North (66%), 152 from Central (26%) and 40 of South (8%).
Results. No significant differences were found among allele distribution.
Conclusion. Chronic PD is a complex disease caused by a combination of genetic susceptibility, patients habits (oral hygiene, smoking, alcohol consumption) and oral pathogens. In our report no differences were detected among three Italian regions in allele distribution.

Vol. X (No. 2) 2017 April-June

  1. MARFAN SYNDROME: ORAL IMPLICATION AND MANAGEMENT
    Bollero P., Arcuri L., Miranda M., Ottria L., Franco R., Barlattani jr. A.
    doi: 10.11138/orl/2017.10.2.087
  2. UNEXPECTED ARTEFACTS AND OCCULT PATHOLOGIES UNDER CBCT
    Lombardo L., Arreghini A., Guarneri M.P., Lauritano D., Nardone M., Siciliani G.
    doi: 10.11138/orl/2017.10.2.097
  3. ORAL HEALTH AND IMPLANT THERAPY IN PARKINSON’S PATIENTS: REVIEW
    Bollero P., Franco R., Cecchetti F., Miranda M., Barlattani jr. A., Dolci A., Ottria L.
    doi: 10.11138/orl/2017.10.2.105
  4. PREGNANCY AND PERIODONTAL DISEASE: DOES EXIST A TWO-WAY RELATIONSHIP?
    Tettamanti L., Lauritano D., Nardone M., Gargari M., Silvestre-Rangil J., Gavoglio P., Tagliabue A.
    doi: 10.11138/orl/2017.10.2.112
  5. POST EXTRACTIVE IMPLANT: EVALUATION OF THE CRITICAL ASPECTS
    Tettamanti L., Andrisani C., Andreasi Bassi S., Vinci R., Silvestre-Rangil J., Tagliabue A.
    doi: 10.11138/orl/2017.10.2.119
  6. IMMEDIATE LOADING IMPLANTS: REVIEW OF THE CRITICAL ASPECTS
    Tettamanti L., Andrisani C., Andreasi Bassi M., Vinci R., Silvestre-Rangil J., Tagliabue A.
    doi: 10.11138/orl/2017.10.2.129
  7. CURING EFFECTIVENESS OF SINGLE-PEAK AND MULTI-PEAK LED LIGHT CURING UNITS ON TPO-CONTAINING RESIN COMPOSITES WITH DIFFERENT CHROMATIC CHARACTERISTICS
    Conte G., Panetta M., Mancini M., Fabianelli A., Brotzu A., Sorge R., Cianconi L.
    doi: 10.11138/orl/2017.10.2.140
  8. EFFECTS OF LIGHT-EMITTING DIODE (LED 640NM) ON HUMAN GINGIVAL FIBROBLASTS: A COMPARATIVE IN VITRO STUDY
    Mandrillo P.M., Fischetto G., Odorisio P., Cura F., Avantaggiato A., Carinci F.
    doi: 10.11138/orl/2017.10.2.151
  9. LONG-TERM PERIODONTAL STATUS OF PALATALLY AND BUCCALLY IMPACTED CANINES AFTER CLOSED SURGICALORTHODONTIC APPROACH
    Bollero P., Danesi C., Ricchiuti M.R., Milazzo A., Mampieri G., Agrestini C., Mucedero M.
    doi: 10.11138/orl/2017.10.2.162
  10. A NEW IMPLANT-ABUTMENT CONNECTION FOR BACTERIAL MICROLEAKAGE PREVENTION: AN IN VITRO STUDY
    Tettamanti L., Cura F., Andrisani C., Andreasi Bassi M., Silvestre-Rangil J., Tagliabue A.
    doi: 10.11138/orl/2017.10.2.172
  11. EARLY MANDIBULAR CANINE-LATERAL INCISOR TRANSPOSITION: CASE REPORT
    Di Venere D., Nardi G.M., Lacarbonara V., Laforgia A., Stefanachi G., Corsalini M., Grassi F.R., Pettini F.
    doi: 10.11138/orl/2017.10.2.181
  12. DELAYED EXPANSION OF ATROPHIC MANDIBLE (DEAM): A CASE REPORT
    Scarano A., Murmura G., Vantaggiato G., Lauritano D., Silvestre-Rangil J., Di Cerbo A., Lorusso F.
    doi: 10.11138/orl/2017.10.2.190
  13. A NEW SURGICAL AND TECHNICAL APPROACH IN ZYGOMATIC IMPLANTOLOGY
    Grecchi F., Bianchi A.E., Siervo S., Grecchi E., Lauritano D., Carinci F.
    doi: 10.11138/orl/2017.10.2.197
Last Viewed articles: la lista degli ultimi x visitati.
  1. GENETIC SUSCEPTIBILITY AND PERIODONTAL DISEASE: A RETROSPECTIVE STUDY ON A LARGE ITALIAN SAMPLE
    Tettamanti L., Gaudio R.M., Iapichino A., Mucchi D., Tagliabue A.
    doi: 10.11138/orl/2017.10.1.020
credits