Oral & Implantology https://www.oimplantology.org/oimp <p><strong>Oral &amp; Implantology</strong> is an international peer-reviewed journal.</p> <p><strong>Oral &amp; Implantology</strong> is aimed to promoting high-quality research and discussion on the most important developments and innovative ideas in <strong>oral and maxillofacial surgery, oral implantology, oral pathology, translational medicine, regenerative medicine, dental biomaterials and all the dental and maxillofacial topics.</strong></p> <p><strong>Oral &amp; Implantology</strong> accepts to publish novel, impacting, and high-quality research papers, to influence and improve the practice of <strong>medicine and dentistry</strong>.</p> <p>Original Articles and RCTs are welcome; nevertheless, well designed reviews, short communications, conference proceedings and letters to editor are also welcome.</p> <p> </p> Dentistry Intermediary Services srls en-US Oral & Implantology 2035-2468 Dental implants and biological coating: the evolution of osseointegration https://www.oimplantology.org/oimp/article/view/385 <p>Titanium plays a predominant role as the material of choice in dental and orthopedic implants. Currently, surface topography modifications and non-biological/ biological coatings have been integrated into implants to simulate the surrounding biological environment as well as depress the infection/inflammation that may occur. Until now, a variety of implant surface modifications, including physical, chemical, and biological techniques, have been applied to a wide selection of materials to reach these outcomes. Best modifications improve the interaction between implants surface and its surrounding bone tissue helping osseointegration while minimizing bacterial colonization.</p> <p>This review article aims to analyze one specific type of biological implants coating, using growth factors, that can have an important impact on cells behavior both in vivo and in vitro.</p> Giulia Valentini Copyright (c) 2023 Oral & Implantology https://creativecommons.org/licenses/by-nc-nd/4.0 2023-04-29 2023-04-29 15 1 Local bisphosphonates to improve dental implants osteointegration and stability: A systematic review. https://www.oimplantology.org/oimp/article/view/386 <p>The use of bisphosphonates to modulate bone remodeling is a widely accepted therapy. Their use is recommended also in dentistry in a wide variety of pathologies and treatments. For that, we performed a systematic review of the literature according to PRISMA statement. Aim of the present work is to evaluate if bisphosphonates locally administrated could improve primary stability od dental implants. As this therapy seems to enhance implant stability and have no drug related complications, there are a limited number of paper in literature to affirm that this could be an established therapy. For that reason, further studies are needed to establish if this could be a real guideline in implant insertion and management.</p> <p><strong>&nbsp;</strong></p> Silvia D'Agostino Marco Dolci Giulia Valentini Copyright (c) 2023 Oral & Implantology https://creativecommons.org/licenses/by-nc-nd/4.0 2023-04-07 2023-04-07 15 1 Effect of cone-beam computed tomography voxel size on detection of vertical periodontal bone defects. https://www.oimplantology.org/oimp/article/view/297 <p><strong>Objectives: </strong>Finding the best voxel size for discernment of vertical bone defects with minimum patient radiation dose is a priority. This study sought to assess the effect of cone-beam computed tomography (CBCT) voxel size on the detection of vertical bone defects.</p> <p><strong>Materials and Methods: </strong>In this in vitro, experimental study, 31 vertical defects including 2 one-wall, 12 two-wall, and 17 three-wall defects were randomly created in the maxilla and mandible of four sheep skulls with the associated soft tissue using round and needle burs. Forty sound sites were considered as the control group. The CBCT scans were obtained from the skulls with 0.150 and 0.300 mm<sup>3</sup> voxel sizes and 8 x 11 cm<sup>2</sup> field of view (FOV). The images were randomly evaluated by two periodontists and two oral and maxillofacial radiologists, and their findings were recorded. The inter-rater observer agreement (weighted kappa), sensitivity and specificity values were calculated for each voxel size. Comparisons were made using paired t-test.</p> <p><strong>Results: </strong>The two voxel sizes had no notable difference in the detection of one-wall and two-wall defects (P&gt;0.05). But the smaller voxel size was significantly superior for the detection of three-wall defects (P=0.001). The inter-rater observer agreement was unfavorable (kappa &lt; 0.6) for the detection of all three defect types.</p> <p><strong>Conclusion: </strong>In general, increasing the image resolution by decreasing the voxel size increased the sensitivity and decreased the specificity of CBCT for detection of vertical bone defects, and is only recommended for detection of three-wall defects.</p> <p><strong> </strong></p> <p><strong> </strong></p> Nina Rouzmeh Masoumeh Eftekhar Hanieh Kaviani Alireza Akbarzadeh Baghban Copyright (c) 2022 Oral & Implantology https://creativecommons.org/licenses/by-nc-nd/4.0 2022-12-28 2022-12-28 15 1 3 11 Clinical performance of titanium-zirconia tissue-level implants in patients with well-controlled and poorly controlled type 2 diabetes: a cohort study with chair-side assessment of oxidative stress. https://www.oimplantology.org/oimp/article/view/373 <p>Purpose: Diabetes is associated to oxidative stress. This might jeopardize implant therapies. The aim of this cohort study was to investigate the survival and success rates of titanium-zirconia implants in patients with a history of type 2 diabetes (T2DM) according to glycemic control and oxidative stress levels.</p> <p>Methods: Patients with T2DM of ≥2-year duration were allocated to either the well-controlled (HbA1c≤&lt; 53 mmol/mol) or poorly-controlled (HbA1c&gt;53 mmol/mol) groups in a prospective cohort fashion. Patients received titanium implants with a zirconia trans-gingival neck. Then, patients were followed at intervals for at least 1.5 years. Clinical and radiographic parameters describing implant success were collected. Rapid chair-side test for the peripheral blood and salivary oxidative stress were performed with spectrophotometer analysis and measured in U CARR units.<span class="Apple-converted-space">&nbsp;</span></p> <p>Results: Thirty-seven implants in twenty-eight patients have been included in the analysis. The 1-year implant survival and success rates were 100%. No signs or symptoms of mucositis/peri-implantitis were recorded up to the last follow-up visit. The blood test for oxidative stress scored an average value of 367±71.8 U CARR, with no differences on the basis of glycemic control. The average salivary test score for oxidative stress was 2203±364 U CARR, which is within the limits of a healthy range. This<span class="Apple-converted-space">&nbsp; </span>test was found to be higher in diabetic patients showing<span class="Apple-converted-space">&nbsp; </span>poor glycemic control.<span class="Apple-converted-space">&nbsp;</span></p> <p>Conclusion: Tissue level implants with a zirconia neck are a reliable solution in diabetic patients with varying levels of glycemic control and oxidative stress, as long as the general oral health is preserved.&nbsp;</p> Simone Marconcini Enrica Enrica Giammarinaro Joao Andre Correia Alberto Maltagliati Francisco Salvado Ugo Covani Copyright (c) 2023 Oral & Implantology https://creativecommons.org/licenses/by-nc-nd/4.0 2023-04-07 2023-04-07 15 1 Increasing the width of the keratinized mucosa around implants with L-PRF: report of a case and systematic review. https://www.oimplantology.org/oimp/article/view/374 <p>Peri-implant phenotypes is essential for long-term success because a thick biotype can lead to a better resistance against bacterial and mechanical damages. Plastic surgery of the peri-implant site is usually performed in order to gain a greater keratinized mucosa width. The purpose of this study was to evaluate the knowledge in literature about leucocytes platelet-rich fibrin (L-PRF) as an autologous solution to change peri-implant width. A case of L-PRF membranes around dental implants is also reported. The systematic review showed a lack of longitudinal long-term studies and a heterogeneity of protocol to produce L-PRF. At the best of our knowledge, L-PRF could represent a suitable soft tissue substitute to increase keratinized mucosa surrounding dental implants.</p> Silvia D'Agostino Marco Grieco Giulia Valentini Sorana Andreea Stoica Marco Dolci Copyright (c) 2023 Oral & Implantology https://creativecommons.org/licenses/by-nc-nd/4.0 2023-04-07 2023-04-07 15 1 Prosthetic rehabilitation of combined facial defect resulting after arteriovenous malformation. https://www.oimplantology.org/oimp/article/view/300 <div class="page" title="Page 1"> <div class="section"> <div class="layoutArea"> <div class="column"> <p>This clinical report details the rehabilitation of a patient who underwent surgical treatment of arteriovenous malformation located in facial tissues. The treatment led to extensive facial defect including orbital region, nose, zygomatic arch, part of maxilla. Prosthetic re habilitation was chosen in order to improve esthetics. With the aid of prosthesis retention 5 extraoral implants were placed. In spite of <span style="font-size: 0.875rem;">wrong position of 1 implant, complex configuration of the defect, expressed vascular pattern on the skin surround defect, impermanent swelling of the facial tissues, appropriate result was achieved.</span></p> </div> </div> </div> </div> Ksenia Veselova Natalia Gromova Irina Antonova Igor Kalakutskii Copyright (c) 2022 Oral & Implantology https://creativecommons.org/licenses/by-nc-nd/4.0 2022-12-28 2022-12-28 15 1 Correlates of knowledge and attitude towards dental implants: A cluster-sampling survey among general dental practitioners in the Asian macro-area. https://www.oimplantology.org/oimp/article/view/299 <p>This study identifies the knowledge levels and attitude towards dental implants among general dental practitioners (GDPs). All registered GDPs in the State of Kuwait were invited to participate in this study. The questionnaire gathered information about the respondents’ demographics, dental education, knowledge about dental implants, self-rating of implant competency and attitude towards dental implants. Multivariable linear regression analysis was performed to investigate the contribution of individual variables to the overall knowledge and attitude scores. Of the 1771 dentists invited to participate in this study, 467 (26.3%) participated in the survey. Cronbach’s alpha knowledge score and attitude score was 0.716 and 0.798, respectively, indicating good internal consistency. The mean ± SD knowledge score was 6.68 ± 2.4 and the mean attitude score was 4.63 ± 5.9. Multivariable analysis showed that years of clinical experience, place of work, region of post-graduate training and self-rated implant competency were significantly associated with the attitude score (p&lt;0.001); and, years of clinical experience, specialty training, region of graduation, advanced dental implant training, and self-rated implant competency were significantly associated with the knowledge score (p&lt;0.001). The level of knowledge about dental implants was low and the respondents lacked the confidence to incorporate dental implants into their routine practice.</p> Dena Ali Halima Al Haid Jagan Kumar Baskaradoss Copyright (c) 2022 Oral & Implantology https://creativecommons.org/licenses/by-nc-nd/4.0 2022-12-28 2022-12-28 15 1 12 24 The next challenges of dentistry: Between interdisciplinary training and precompetitive scientific research. https://www.oimplantology.org/oimp/article/view/298 <p>This Editorial by Prof. Marco Tatullo, from University of Bari (Italy), aims to point out a brief overview on the most intriguing innovations impacting on the future of dentistry.</p> Marco Tatullo Copyright (c) 2022 Oral & Implantology https://creativecommons.org/licenses/by-nc-nd/4.0 2022-12-28 2022-12-28 15 1 1 2