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HISTOLOGIC AND HISTOMORPHOMETRIC ANALYSIS OF MAXILLARY SINUS AUGMENTATION WITH DIFFERENT BIOMATERIALS. A PILOT SPLIT-MOUTH HUMAN STUDY

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Abstract

Objectives. The aim of this pilot split-mouth controlled human study is to evaluate histologic and histomorphometric results of a highly purified xenogenic grafting material in maxillary sinus floor augmentation after six months of follow-up. Methods. This pilot split-mouth study was conducted on 11 patients, 7 females and 4 males (mean age 53 +/- 7.9 years; range 41-68 years), who underwent maxillary sinus floor augmentation. The following biomaterials were used: Laddec: a highly purified bovine xenograft, that was the test material; and Bio-oss a natural bone mineral, that was the control material. Six patients (4 females, 2 males) were treated with unilateral major maxillary sinus floor augmentation with Bio-oss, and five patients (3 females, 2 males) were subjected to bilateral major maxillary sinus floor augmentation, with Bio-oss in one side and Laddec in the other side. Consequently, the test group (Laddec) included 5 samples, while the control group (Biooss) included 11 samples. Results. For the Laddec, the newly formed bone was 36% ± 2.3; the intertrabecular spaces were 34% ± 1.6, and the residual material was 30% ± 1.4. For the Bio-Oss, the newly formed bone was 38% ± 1.6; the intertrabecular spaces were 26% ± 1.6, whereas the residual material was 36% ± 3.1. Conclusions. Both the xenoimplants obtained a good bone regeneration with a satisfying quantity of newly formed bone and reduced quantity of fibrous bone. The Laddec showed a better absorbability compared with Bio-Oss, whose residual percentage is greater for the same elapsed time.

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Authors

S. Mummolo

A. Nota

E. Marchetti

S. Capuano

S. Tecco

G. Marzo

V. Campanella

How to Cite
Mummolo , S., Nota , A., Marchetti, E., Capuano , S., Tecco , S., Marzo , G., & Campanella , V. (2018). HISTOLOGIC AND HISTOMORPHOMETRIC ANALYSIS OF MAXILLARY SINUS AUGMENTATION WITH DIFFERENT BIOMATERIALS. A PILOT SPLIT-MOUTH HUMAN STUDY. Oral & Implantology, 11(4), 249–256. Retrieved from https://www.oimplantology.org/oimp/article/view/271
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